Abstract:Objective To compare the application effect of forearm free flap and anterolateral thigh free flap in repairing the postoperative defects of head and neck carcinoma. Methods Forty patients were divided into the forearm free flap group and the anterolateral thigh free flap group according to the random number table method, who had soft tissue defects after the patients received treatment of head and neck squamous cell carcinoma surgery from January 2019 to December 2022. One group was repaired by forearm free flap, and the other group by anterolateral thigh free flap. The survival rate of flaps, the incidence of complications and other surgery-related conditions were compared between the two groups. Results There was no statistically significant difference in the survival rate of flaps, flap preparation time, operation time, ICU observation time, and postoperative hospital stay between the two groups (P>0.05).The incidence of postoperative complications in forearm free flap was higher than that in the anterolateral thigh free flap group.The difference was statistically significant (P<0.05). Conclusions Both forearm free flap and anterolateral thigh free flap have good flap survival rate(95%),which are prior choices for repairing the soft tissue defects after surgery for head and neck squamous cell carcinoma. There are individual advantages for both in clinical practices ,the selection of appropriate flap repair should be made according to the specific situations of patients and doctors.