零回波时间磁共振成像在鼻咽癌颅底骨侵犯的临床评价*

Clinical Evaluation of Zero-Echo-Time MR Imaging for Skull Base Invasion in Nasopharyngeal Carcinoma

摘要:

目的 探讨零回波时间(zero echo time, ZTE)磁共振成像技术对鼻咽癌颅底骨侵犯的价值及其对肿瘤分期的影响。方法 分析本院治疗前鼻咽癌患者69例,男50例,女19例,运用GE Discovery 750W 3.0T MR扫描仪,获取常规平扫+增强扫描,利用ZTE-MR成像技术获取ZTE-MR图像,比较分析ZTE-MR成像技术与MRI常规扫描技术两种成像方法对于鼻咽癌颅底骨侵犯的价值。采用卡方检验分析MRI常规图像、ZTE-MR成像的阳性检出率。结果 ZTE-MR成像技术、MRI常规扫描技术这两种成像方法对于鼻咽癌颅底骨侵犯存在差异,ZTE-MR成像的阳性检出率为91.30%(63/69),MRI常规图像的阳性检出率78.26%(54/69),具有统计学意义(P＜0.05)。结论 ZTE-MR成像可以提高对颅底骨侵犯诊断的准确性,有效影响肿瘤分期。

关键词:鼻咽癌;磁共振成像;颅底

Abstract:

Objective: To study Zero-Echo-Time MR Imaging on skull base bone invasion in nasopharyngeal carcinoma and its effect on tumor staging. Methods: To analyze 69 patients with nasopharyngeal carcinoma ,50 men and 19 women, using the GE Discovery 750W 3.0T MR scanner to obtain unenhanced scan and enhanced scan, using ZTE-MR imaging technology to obtain ZTE-MR image. The value of two imaging methods, ZTE-MR imaging and MRI conventional imaging, for skull base bone invasion in nasopharyngeal carcinoma was compared. Using chi-square test to analyze the positive detection rate of MRI standard imaging and ZTE-MR imaging. Results: The two imaging methods, ZTE-MR imaging and MRI conventional imaging, were different for skull base bone invasion in nasopharyngeal carcinoma. The positive detection rate of ZTE-MR imaging was 91.30%(63/69), and the positive detection rate of MRI conventional imaging was 78.26%(54/69), which was statistical significance (P<0.05). Conclusion: ZTE-MR imaging can improve the accuracy of diagnosis of skull base bone invasion and effectively affect tumor staging.

Key words:Nasopharyngeal Carcinoma; Magnetic resonance imaging; Skull base