不同方法治疗早期声门型喉癌的疗效对比分析

A comparative analysis on the curative effects of different treatment for early glottic laryngeal carcinoma patients

摘要:

目的 研究早期声门型喉癌患者行不同方法治疗的效果。方法 选取60例早期声门型喉癌患者，根据治疗方法不同分为3组，其中A组(支撑喉镜下CO₂激光术，n=20)、B组(低温等离子射频消融术，n=20)、C组(喉切除术，n=20)，对3组患者进行疗效比较。结果 3组患者并发症、复发率经比较差异无统计学意义(P>0.05)。与A、C组比较，B组手术时间更短，术中出血量更少，视觉模拟评分(VAS)、黏膜恢复评分更低，首次经口进食时间、首次发声时间及住院天数更短，喉功能改善率更高，经比较差异均具有统计学意义(P均<0.05)。结论 早期声门型喉癌患者行低温等离子射频消融术及CO₂激光术可改善喉部功能、减轻疼痛，促进创面黏膜恢复、缩短疗程，值得临床推广应用。

Abstract:

Objective To study the effect of different treatment for early glottic laryngeal carcinoma. Methods Sixty patients with early glottic laryngeal carcinoma were divided into group A (CO₂ laser with support laryngoscope, n=20) and group B (low-temperature plasma radiofrequency ablation, n=20) and group C (laryngectomy, n=20). the curative effect of the three groups was compared. Results There was no significant difference in the complication and recurrence rate among the three groups (P>0.05)， compared with group A and group C, group B had shorter operation time, less intraoperative blood loss, lower visual analogue scale(VAS) and mucosal recovery scores. First oral eating, first vocalization and hospital stay were shorter; the improvement rate of laryngeal function was higher, and the differences were statistically significant (all P<0.05). Conclusion Low-temperature plasma radiofrequency ablation and CO₂ laser in patients with early glottic laryngeal carcinoma can improve laryngeal function, relieve pain, promote the recovery of wound mucosa, and shorten the course of treatment, which is worthy of clinical application.