Abstract:Objective To preliminarily analyze the safety and cosmetic effects of Hybrid-transoral endoscopic thyroidectomy submental access (H-TOETSA) for male patients with thyroid tumors.Methods Clinical data of 55 male patients,undergoing thyroid tumor surgery from September 2021 to April 2022 were collected. Among them, 30 patients underwent H-TOETSA (experimental group), while 25 patients underwent thyroid surgery via traditional “collar style” neck skin incision (control group) during the same period. The general information, clinical parameters (surgical time, postoperative drainage volume, postoperative hospital stay), and complications (recurrent laryngeal nerve injury, permanent hypothyroidism, infection, and chin numbness) between the two groups were compared. The patient satisfaction with cosmetic outcomes was assessed one month after surgery.Results Compared with the control group, the experimental group had longer surgical time (153.233±40.826 vs 122.960±37.821) and shorter postoperative hospitalization days (2.733±0.907 vs 3.480±1.005), and the differences were statistically significant (P<0.05). There were no statistically significant differences in postoperative mental numbness, postoperative drainage volume and complications between the two groups (P>0.05). The subjective cosmetic satisfaction of the experimental group was significantly higher than that of the control group (8.733±0.450 vs 7.680±0.476, P=0.000).Conclusion Without safety disadvantages, the H-TOETSA is suitable for male thyroid tumor patients with cosmetic needs.