Abstract:Objective To investigate the clinical characteristics and prognostic factors of sudden sensorineural hearing loss in middle-young-aged people.Methods A total of 147 patients with sudden sensorineural hearing loss admitted to in the department of Otolaryngology, the Fourth Affiliated Hospital of Guangzhou Medical University, from June 2020 to May 2022 were selected. According to the age of the patients, they were divided into experimental group (n=74) aged 18-55 years old and control group (n=73) aged 56-80 years old. The clinical data of the two groups of sudden sensorineural hearing loss patients were retrospectively analyzed, and the clinical characteristics and prognosis of the two groups were compared.Results There was no significant difference in the general condition between the two groups(P>0.05).There was no significant difference in clinical symptoms such as tinnitus, ear tightness and vertigo between the two groups(P>0.05). The grade, type and clinical efficacy of hearing loss were compared. The hearing loss in the experimental group was mild. The low frequency drop type was relatively more common, the total effective rate of clinical treatment was higher, and the differences were statistically significant (P all<0.05). Incidence rate of sudden deafness in patients with hypertension, diabetes, cerebrovascular diseases, etc, the prevalence of the experimental group was significantly lower than that of the control group (P all<0.05).Conclusions Middle-young-aged patients with sudden sensorineural hearing loss have the clinical characteristics of less basic diseases, less hearing damage, and relatively common low-frequency decline type. Through clinical active treatment, the curative effect is often significant and the prognosis is good.