奥密克戎变异株感染患者合并咽痛的临床特征分析

Clinical manifestations and characteristics of complicated pharyngalgia in patients infected with Omicron variant strain

摘要:

目的 观察奥密克戎变异株患者合并咽痛及其特征分析。方法 收集2022年4月18日—2022年5月30日上海市中医药大学附属曙光医院西院定点医院感染一科一病区142例奥密克戎变异株感染患者的临床资料，根据咽痛程度分级评分、咽痛出现时间、咽痛持续时间、咽痛引起的心理状况、咽痛消失后咽部不适症状持续时间等情况，分析患者的临床特点。结果 在纳入的142例奥密克戎变异株感染患者中轻型111例(78.2%)、普通型27例(19.0%)、重型4例(2.8%)；各组间咽痛程度分级、咽痛出现时间差异均无统计学意义(P>0.05)；重型组咽痛持续时间、咽痛消失后咽部不适症状持续时间明显延长，与轻型组和普通型组比较差异均具有统计学意义(P<0.05),普通型组咽痛持续时间最短，与轻型组比较差异具有统计学意义(P<0.05)；在疼痛引起的心理状况观察中轻型组较严重，与其他两组比较差异具有统计学意义(P<0.05)。结论 奥密克戎变异株感染患者的临床症状中咽痛较为明显，且影响患者发病期间生活质量、营养饮食和疾病康复，因此临床医师不能忽视奥密克戎变异株感染患者咽痛的治疗和改善。

关键词:咽痛;奥密克戎变异株;临床分析

Abstract:

Objective To observe the clinical manifestations and characteristics of complicated pharyngalgia in patients infected with Omicron variant strain of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2).Methods Clinical data of 142 patients infected with omicron variant strain were collected from April 18, 2022 to May 30, 2022 in the ward of the designated hospital of Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. The clinical characteristics were analyzed according to the grading score, occurrence time and duration of pharyngalgia, the psychological status caused by pharyngalgia, as well as the duration of pharyngeal discomfort after the disappearance of pharyngalgia.Results Among the 142 patients, 111 cases (78.2%) were mild, 27 (19.0%) were common, and 4 (2.8%) were severe. There were no significant differences in the occurrence time and grade of pharyngalgia among all groups (P>0.05). The duration of pharyngalgia and the duration of pharyngeal discomfort after the disappearance of pharyngalgia in the severe group were significantly longer than those in the mild group and the common group, and the differences were statistically significant (P<0.05). The duration of pharyngalgia in the common group was the shortest, and there was significant difference compared with the mild group (P<0.05). The psychological status caused by pharyngalgia of the mild group was worse than those of the other two groups, and the differences were statistically significant (P<0.05).Conclusions Pharyngalgia is obvious in patients infected with Omicron variant strain of SARS-COV-2, and affects their quality of life, nutritional diet and disease rehabilitation. Clinicians should not ignore the treatment and relief of pharyngalgia in these patients.

Key words:Pharyngalgia;Omicron variant;Clinical analysis