Abstract:Objective To summarize and analyze the clinical data of petrous cholesteatoma of temporal bone, and to explore the diagnosis and treatment strategy of different types of petrous cholesteatoma.Methods Thirty-two cases of petrous cholestatoma of temporal bone were retrospectively analyzed. According to the Sanna classification, the 32 patients were divided into superior labyrinthous type (10 cases), inferior labyrinthous type (11 cases), inferior labyrinthy-petrous apex type (1 case), giant labyrinthous type (9 cases) and petrous apex type (1 case).Different surgical methods are selected according to different the conditions of patients.Evaluation of facial paralysis: 10 cases (31.25%) of the patients had facial paralysis before operation.HB classification of facial paralysis included 1 case of grade Ⅱ, 1 case of grade Ⅲ, 2 cases of grade Ⅳ, 2 cases of grade Ⅴ and 4 cases of grade Ⅵ. There were 21 cases with intracranial and extracranial complications before operation, including 5 cases with brain abscess.To summarize the treatment experience of various types of petrous cholesteatoma.Results None of the 32 patients with petrous bone cholesteatoma died after surgical treatment.On the premise of complete resection of cholesteatoma, one case of huge labyrinthiform cholesteatoma invaded the pontocerebellar angle area with a little residual during operation. The other cases showed no residual lesions under microscope or endoscope.The new complications included Bezold abscess in 1 case, frontotemporoparietal occipital subdural hematoma in 1 case, cerebrospinal fluid otorrhea in 1 case, and postoperative facial paralysis in 3 cases, all of which were cured after corresponding treatment. After 6 to 36 months of follow-up, there was one recurrence of superlabyrinthian type and one recurrence of giant labyrinthal type,who were operated again.There were no deaths during follow-up.Conclusions The selection of surgical strategies and surgical methods for petrous bone cholestatoma was very important, which should be comprehensively evaluated according to the classification of lesions, facial nerve function and complications, etc.Under complete removal of lesions and reduced complications,the function of facial nerve and hearing were preserved.