Abstract:Objective To explore the diagnostic and surgical methods of communication tumor of nasal skull base.Methods Clinical data of 37 patients who underwent resection of communication tumor of nasal skull base from Jan 2011 to Dec 2021 in the Department of Neurosurgery, Tongji Hospital, Affiliated Hospital of Tongji Medical College, Huazhong University of Science and Technology were analyzed retrospectively. Of them, 23 were male and 14 were female, aged from 6 to 61 years old with an average of 49. There were 27 cases of malignant tumor and 10 cases of benign tumor. The maximal diameter of the tumor varied from 4.7 to 8.5 cm with an average of 6.3 cm. All cases had a series of preoperative imaging examinations and underwent craniotomy plus skull base reconstruction as well as long-term follow-up. Patients with malignant tumor had been followed up from 5 to 10 years, with a mean of 8.3 years, while those with benign tumor from 1 to 11 years, with a mean of 6.7 years.Results Surgical treatment was completed successfully without major complications in all the patients. The five-year survival rate of the patients with malignant tumor was 63.0%(17/27). Five years after operation, recurrence occurred in one patient with benign tumor (atypical meningioma), and reoperation was performed via bilateral frontal fundus approach.Conclusions The communication tumor of nasal skull base in neurosurgery department mostly locate in the skull. The total or subtotal resection by craniotomy followed with proper skull base reconstruction is of great significance.