慢性鼻窦炎伴鼻息肉患者组织嗜酸性粒细胞与血清特异性IgE的相关性
DOI:
作者:
作者单位:

宁夏银川市第一人民医院

作者简介:

通讯作者:

基金项目:


Analyses of the relationship between eosinophils and serum specific IgE in patients with chronic rhinosinusitis
Author:
Affiliation:

Hu jingmin

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
    摘要:

    目的 分析慢性鼻窦炎伴鼻息肉患者组织嗜酸性粒细胞与血清特异性IgE的关系及其临床特征。方法 选取2019年6月至2021年6月行功能性鼻窦内窥镜手术的192例慢性鼻窦炎伴鼻息肉患者,根据血清特异性IgE监测结果分为SIgE阳性组和SIgE阴性组,比较两组患者组织嗜酸性粒细胞计数、术前VAS评分、Lund-Mackay CT评分及Lund—Kennedy 评分。结果 两组在性别,年龄及VAS评分比较无统计学意义(P>0.05);SIgE阳性与否和ECRS是否浸润在例数上比较无统计学差异(P>0.05);在临床学特征方面,SIgE阳性ECRS浸润组和其它三组比较在术前VAS评分,Lund-Mackay CT评分及Lund—Kennedy 评分有统计学差异。结论 慢性鼻窦炎伴鼻息肉患者组织嗜酸性粒细胞浸润程度与过敏反应不呈正相关;患者ECRS浸润同时合并SIgE阳性主客观症状加重。

    Abstract:

    Objective To analyze the relationship between eosinophils and serum specific IgE in patients with chronic rhinosinusitis with polyposis and their clinical characteristics. Methods?? 192 patients with chronic rhinosinusitis with nasal polyp who underwent functional endoscopic sinus surgery from June 2019 to June 2021 were selected and divided into SIgE-positive group and SIgE-negative group based on the results of serum-specific IgE monitoring. The eosinophil count, preoperative VAS score, Lund-Mackay CT score, and Lund- Kennedy score were compared between the two groups. Results: There was no statistical significance in gender, age and VAS scores between the two groups (P>0.05); There was no statistical difference in the number of cases between SIgE-positive and whether ECRS is infiltrated (P>0.05); In terms of clinical characteristics, there were significant differences in preoperative VAS score, Lund-Mackay CT score and Lund-Kennedy score between SiGe-positive ECRS infiltration group and the other three groups. CONCLUSIONS? There is no positive correlation between the infiltration degree of eosinophil and allergic reaction in patients with chronic rhinosinusitis with nasal polyp; The subjective and objective symptoms of patients with chronic rhinosinusitis with nasal polyp were aggravated when the ECRS infiltration coexistedwith SIgE-positive.

    参考文献
    相似文献
    引证文献
引用本文
分享
文章指标
  • 点击次数:
  • 下载次数:
历史
  • 收稿日期:2022-04-29
  • 最后修改日期:2022-06-13
  • 录用日期:2022-06-22
  • 在线发布日期:
新投稿系统运行通知

作者投稿请直接点击左侧“作者登录”,请不要进入旧版入口。如登录或投稿中遇到任何问题,请联系电话13311390237。谢谢!

关闭