啮蚀艾肯菌致鼻咽颅底感染1例报道

Nasopharynx and skull base infection caused by Eikenella corrodens: a case report

摘要:

目的 总结1例啮蚀艾肯菌引起鼻咽颅底感染的诊疗经验，提高对该菌感染病的认识。方法 回顾性分析1例啮蚀艾肯菌致鼻咽颅底感染患者的病例资料，并结合文献进行讨论。结果 本例患者完善内镜检查、影像学检查以及实验室检查，鼻咽颅底组织2次病理报告均为慢性肉芽肿性炎，经实验室确诊为啮蚀艾肯菌感染，予清创引流、口服抗生素2个月后，患者痊愈，术后随访3个月未复发。结论 鼻咽颅底感染临床少见，临床症状、影像学检查与鼻咽癌相似。啮蚀艾肯菌为罕见致病菌，发病率低。诊治上，需结合病理学、病原学检查明确诊断，及早清创引流、选取合适的抗感染药物。

Abstract:

Objective To summarize the diagnostic and therapeutic experience of a case about nasopharynx and skull base infection caused by Eikenella corrodens, and to improve the understanding of this bacterial infection.Methods The case data of a patient with nasopharynx and skull base infection caused by Eikenella corrodens suspected of nasopharyngeal carcinoma were retrospectively analyzed and discussed in combination with the literature.Results The patient underwent endoscopic examination, imaging examination and laboratory examination were completed in this case. Two pathological reports of nasopharyngeal skull base tissue were chronic granulomatous inflammation. The patient was confirmed to be infected with the infection of Eikenella corrodens by laboratory. The patient was cured after 2 months of debridement and drainage and oral antibiotics, and there was no recurrence after 3 months of follow-up.Conclusions Nasopharynx and skull base infection is rare in clinic. The clinical symptoms and imaging findings of this infection are similar to those of nasopharyngeal carcinoma. The incidence rate of Eikenella corrodens is very low. In the diagnosis and treatment of this infection, it is necessary to make a definite diagnosis combined with pathological and etiological examination. The debridement and drainage and appropriate anti-infective drugs should be selected as soon as possible.