青少年鼻咽癌2例报道并文献复习

Juvenile nasopharyngeal carcinoma: 2 cases and literature review

摘要:

目的 探讨青少年鼻咽癌的临床诊治经验。方法 回顾性分析2例青少年鼻咽癌患者的病例资料，并结合文献进行复习，进而对该类患者发病的临床特点、诊断与治疗进行讨论。结果 本文2例患者在初诊时均被误诊，诊治过程中因其疾病特点与常见疾病不相符，但与鼻咽癌特点相似，行鼻咽部活检，最后病理报告均证实为鼻咽癌，确诊后行放疗为主的综合治疗。结论 青少年鼻咽癌患者在临床上少见，发展快，初诊时易误诊，临床医生除考虑常见病的诊断外，还需警惕鼻咽癌的可能，做到早发现、早诊断、早治疗，提高患者的生存率。

Abstract:

Objective to explore the clinical experience of diagnosis and treatment of juvenile nasopharyngeal carcinoma (NPC).Methods The clinical data of 2 cases of juvenile NPC were retrospectively analyzed. The clinical characteristics, diagnosis and treatment of this kind of patients were reviewed and discussed.Results Both patients in this paper were misdiagnosed at initial diagnosis. During the diagnosis and treatment of the patients, because the characteristics of the disease were not consistent with common diseases, but similar to NPC, nasopharyngeal biopsy was performed. Finally, the pathological report confirmed that the samples of nasopharyngeal biopsy were NPC. After diagnosis of NPC, they were given comprehensive treatment based on radiotherapy.Conclusions Clinical juvenile NPC patients were rare and develop rapidly. It is easy to be misdiagnosed at initial diagnosis. Clinicians should not only consider the diagnosis of common diseases, but also be alert to the possibility of NPC. And clinical NPC should be detected, diagnosed and treated early to improve the survival rate of patients.