Abstract:Objective To investigate and summarize the method and effect of protecting sphenoparietal sinus drainage vein in the operation of middle cranial fossa meningioma.Methods The clinical data of 27 patients with middle cranial fossa meningiomas were retrospectively analyzed, who underwent neurosurgery in Sanbo Brain Hospital, Capital Medical University from June 2008 to June 2019. There were 10 males and 17 females, aged from 30 to 67 years, with an average age of 55.5 years. The duration of disease lasted from 4 months to 3 years. Of the 27 patients, 15 cases had superior drainage of sphenoparietal sinus and 12 cases had non dominant drainage. Tumor resection was performed in all 27 patients via frontal-temporal interfascial approach.Results Simpson Grade Ⅱ resection was achieved in 24 cases and Simpson Grade Ⅲ resection in 3 cases. During the operation, 3 cases with non dominant drainage veins were cut off by electrocoagulation due to tumor wrapping and adhesion. One case underwent secondary operation to remove the bone flap decompression due to edema. All the patients had been followed-up postoperatively for 2 to 13 years with an average of 5.5 years. No tumor recurrence occurred, and no patients died during the operation.Conclusions Meningiomas in the middle cranial fossa often involves the drainage vein of the sphenoparietal sinus. The venous drainage should be evaluated carefullly before operation. More attention should be paid to the protection of the vein. Postoperative cerebral edema can be alleviated by sharp dissection and preservation of drainage veins.