29例外伤性大脑半球间硬膜下血肿的临床分析
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国家自然科学基金青年基金项目(81602204,81801235)。


Clinical analysis of 29 patients with traumatic interhemispheric subdural hematoma
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    摘要:

    目的 探讨外伤性大脑半球间硬膜下血肿(TISH)的治疗方法和预后。方法 回顾性分析华中科技大学同济医学院附属同济医院2014年8月—2019年5月收治的29例TISH患者的临床资料。患者治疗后2周由Glasgow预后量表(GOS)评估短期疗效。GOS 1~3分为疗效差,GOS 4~5分为疗效好。结果 疗效良好者20例,占69.0%,疗效差者9例,占31.0%。疗效好组治疗后2周Glasgow昏迷评分(GCS)平均为(14.6±0.7)分,疗效差组为(9.4±2.2)分,两组间比较差异具有统计学意义(P<0.001)。单因素分析显示影响TISH疗效的因素包括合并合并脑挫裂伤(P=0.032),入院时GCS评分(P<0.001),住院期间病变变化(P=0.049),住院期间GCS极低值(P<0.001),治疗方式(P=0.016)和手术方式(P<0.05)。重症TISH患者(GCS≤8分)中7例行手术治疗,3例非手术治疗。手术组预后良好者4例,预后差者3例;而非手术组3例患者短期预后均较差。结论 TISH临床少见,多数患者病情较轻经保守治疗效果较好。部分患者出现迟发性出血,颅内压增高,神经功能障碍等,需严密监护。重症TISH患者手术治疗能够改善预后。

    Abstract:

    Objective To explore the the treatment and prognosis of patients with traumatic interhemispheric subdural hematoma (TISH).Methods the clinical data of 29 TISH patients admitted to Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology from August 2014 to May 2019 were retrospectively analyzed. Short-term outcomes were assessed by the Glasgow Outcome Scale (GOS) at two weeks after treatment. GOS 1~3 was poor, and GOS 4~5 was good.Results The good curative effect was achieved in 20 cases (69.0%), while the poor outcome was identified in 9 cases (31.0%). The mean GCS was (14.6±0.7) points in good outcome group and (9.4±2.2) points in the poor treatment group at two weeks after treatment, the difference between the two groups was statistically significant (P<0.001). Univariate analysis demonstrated various factors affecting the TISH outcome including cerebral contusion (0.032), GCS score at admission (P<0.001), GCS score decreased during hospitalization (P=0.049), and extreme GCS value during hospitalization (P<0.001), treatment (P=0.016) and surgical approach (P<0.05). In severe TISH patients (GCS ≤ 8), 7 patients were treated surgically and three cases received non-surgical treatment. The short-term outcome in surgery group, 4 cases had good prognosis, and 3 cases had poor prognosis.Conclusion The incidence of TISH was rare. Most TISH was mild illness, who might achieve a good outcome by medication treatment. Similarly, a good outcome could be obtained by neuro-monitoring and neurosurgical treatment in some severe cases with delayed hemorrhage, increased intracranial pressure and nerve dysfunction.

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孙道法,万学焱,李宇,雷晋,韩林,赵恺,牛洪泉,舒凯,雷霆.29例外伤性大脑半球间硬膜下血肿的临床分析[J].中国耳鼻咽喉颅底外科杂志,2022,28(3):61-65

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  • 收稿日期:2021-06-09
  • 在线发布日期: 2022-07-04
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