Abstract:Objective To investigate the causes of misdiagnosis, clinical diagnosis and pathological characteristics of glomus jugulare-tympanicum paraganlioma.Methods The clinical data of a rare glomus jugulare-tympanicum paraganlioma admitted to our hospital were reviewed retrospectively, and the clinical and pathological characteristics of the glomus jugulare-tympanicum paraganlioma were discussed.Results The patient’s CT showed the right external auditory canal, mastoid air chamber, mastoid sinus, and tympanic soft tissue shadows, corresponding bone resorption and destruction. Combined with medical history, and chronic middle ear mastoiditis with cholesteatoma formation was considered, and the right jugular bulb was elevated. The mass was removed by a retroauricular approach. Due to much intraoperative bleeding, the mass was not completely removed. Based on pathological examination results, the tympanic jugular paraganglioma was diagnosed. The patient has not been further treated. Reviewing the literature, glomus jugulare-tympanicum paraganlioma is rare, and the clinical and imaging examinations are not specific. Due to the lack of large sample follow-up studies, the prognosis is unknown.Conclusions Relying solely on symptoms and characteristics, glomus jugulare-tympanicum paraganlioma is easy to be misdiagnosed as secretory otitis media or cholesteatoma. The analysis of CT, MR, DSA, and detailed histopathology are the main methods for diagnosis and identification of glomus jugulare-tympanicum paraganlioma.