血液指标与突发性耳聋预后的相关性研究

Study on the Correlation between Blood Index and Prognosis of Sudden Deafness

摘要:

目的 通过回顾性研究，分析血液指标与突发性耳聋患者听力损失严重程度、分型及预后的相关性，初步探索突发性耳聋患者相关的微循环因素，为临床治疗提供参考。方法 收集2019年9月～2021年4月山西医科大学第一医院143例突发性耳聋患者住院资料，利用SPSS21.0统计软件进行统计学分析，各参数指标与突发性耳聋严重程度、分型及预后采用单因素ANOVA分析，采用LSD进行两两比较，多因素logistic回归分析各差异指标与突发性耳聋患者预后之间的关系。结果 APTT值（P=0.033）、NLR值（P=0.017）、突聋时间（P=0.003、=-0.062，OR=0.940）、平坦下降型（P=0.019、=-1.806，OR=0.164）、轻度（P=0.017）及中度（P=0.034、=-1.745，OR=0.175）等因素与突发性耳聋患者疗效相关，P<0.05，差异有统计学意义。结论 APTT值、NLR值与突发性耳聋患者预后有关，突聋时间、听力严重程度及听力曲线平坦下降型可独立影响患者的疗效，突聋时间越短、听力严重程度越轻，预后越好，患者听力曲线呈平坦下降型较其他类型曲线预后更好。

Abstract:

Objective To analyze the correlation between blood indicators and the severity, classification and prognosis of hearing loss in patients with sudden deafness through retrospective research, and to initially explore the microcirculation factors related to patients with sudden deafness, so as to provide references for clinical treatment. Methods The hospitalization data of 143 patients with sudden deafness in the First Hospital of Shanxi Medical University from September 2019 to April 2021 were collected, and statistical analysis was carried out using SPSS21.0 statistical software. Each parameter index was related to the severity and score of sudden deafness. The type and prognosis were analyzed by single-factor ANOVA, LSD was used for pairwise comparison, and multivariate logistic regression was used to analyze the relationship between the different indicators and the prognosis of patients with sudden deafness. Results APTT value (P=0.033), NLR value (P=0.017), sudden deafness time (P=0.003, =-0.062, OR=0.940), flat decline type (P=0.019, =-1.806, OR=0.164) Factors such as mild (P=0.017) and moderate (P=0.034, =-1.745, OR=0.175) are related to the curative effect of patients with sudden deafness, P<0.05, the difference is statistically significant. Conclusion The APTT and NLR values ??are related to the prognosis of patients with sudden deafness. The duration of sudden deafness, hearing severity, and the flat-declining hearing curve can independently affect the patient's curative effect. The shorter the sudden deafness time and the less severe the hearing, the better the prognosis. , The patient’s hearing curve is flat and has a better prognosis than other types of curves.