北京大学第三医院 北京 100191
首都卫生发展科研专项 鼻腔微创支架的设计与应用 首发2020-2Z-40918
目的：通过对比观察鼻腔支架与膨胀海绵应用于鼻中隔矫正术后填塞的临床效果及舒适度,探究鼻腔支架临床应用的安全性及有效性。方法：选择因鼻中隔偏曲行鼻中隔偏曲矫正术患者56例,按填塞方式随机分为鼻腔支架组(实验组 26例)和膨胀海绵组(对照组 30例),比较两组填塞期止血效果、舒适度及并发症情况。结果：实验组有效率69%,对照组有效率60%,差异无统计学意义(x2=0.517, P=0.472),术后VAS评分均值实验组鼻塞,鼻痛,头痛,溢泪,面部胀痛,吞咽困难,睡眠障碍,口干及总体不适均小于对照组(P<0.05),差异有统计学差异。实验组及对照组均未出现鼻中隔穿孔、鼻中隔血肿及感染等并发症。结论：鼻腔支架作为鼻中隔矫正术后新型填塞方式安全有效,舒适度优于膨胀海绵填塞,可进一步应用于临床。
Objective: To investigate the safety and effectiveness of nasal stent in clinical application by comparing and observing the clinical effect and comfort of nasal stent and merocel sponge applied in nasal septoplasty. Methods: 56 patients with nasal septal deviation were selected and randomly divided into nasal stent group (experimental group, 26 cases) and merocel sponge group (control group, 30 cases) according to the packing method. The hemostasis effection, comfort and complications of the two groups were compared during the packing period. Results: The effective rate of the experimental group was 69%, and that of the control group was 60%, with no statistically significant difference (X2 =0.517, P=0.472). The mean postoperative VAS scores of the experimental group were all lower than those of the control group (P<0.05). No septal perforation, septal hematoma and infection were found in the experimental group and the control group. Conclusion: Nasal stent is safe and effective as a new packing method after nasal septal correction. It is more comfortable than expansive sponge packing, and can be further applied in clinical practice.