Abstract:Objective To investigate the recurrence factors of benign paroxysmal positional vertigo (BPPV) after reduction therapy, and to analyze the standing balance function of BPPV patients. Methods 209 BPPV patients (BPPV group) admitted to the otolaryngology Department of our hospital from February 2019 to December 2020 were selected. All patients received regular telephone follow-up after manual reduction treatment, and were divided into recurrence group (48 cases) and non-recurrence group (161 cases) according to whether recurrence occurred during follow-up. By collecting clinical data, the risk factors for recurrence of BPPV were analyzed by multivariate Logistic regression. The sensory organization test (SOT) and the modified clinical test of sensory interaction and balance (mCTSIB) were used to evaluate static standing balance. The difference of dynamic and static standing balance function between BPPV patients with different semicircular canal involvement and control group was compared. Results The proportion of age ≥50 years old, female, hypertension, hyperlipidemia, diabetes, vertigo duration ≥1 week and reduction times ≥3 times in recurrence group were higher than those in non-recurrence group (P < 0.05). Multivariate Logistic regression analysis showed that age ≥50 years old, female, diabetes, hypertension and hyperlipidemia were risk factors for recurrence after manual reduction of BPPV (P < 0.05). The SOT balance score at open eyes - Force plate stability - Visual scene follow-up (CON3), Open eyes - Force plate follow-up - Visual scene stability (CON4), Closed eyes - Force plate follow-up - Visual scene stability (CON5), Open eyes - Force plate follow-up - Visual scene follow-up (CON6) in BPPV group with posterior canal involvement was lower than that in control group (P < 0.05), and the average velocity of center of gravity shaking when standing on sponge pad with eyes open and closed was higher than that in the control group (P < 0.05). Conclusion Advanced age, female, hypertension, hyperlipidemia and diabetes are risk factors for recurrence of BPPV after manual reduction. Patients with BPPV involving posterior semicircular canal are prone to abnormal standing balance function.