啮蚀艾肯菌致鼻咽颅底感染1例报道
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1.广州中医药大学;2.广东省中医院

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Nasopharyngx and skull base infection caused by Eikenella corrodens:a case report
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1.Guangzhou University of Chinese Medicine;2.Guangdong Provincial Hospital of Traditional Chinese Medicine

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    目的 总结1例啮蚀艾肯菌引起鼻咽颅底感染的诊疗经验,提高对该菌感染的认识。方法 回顾性分析1例啮蚀艾肯菌致鼻咽颅底感染患者的病例资料,并结合文献进行讨论。结果 本例患者完善内镜检查、影像学检查以及实验室检查,鼻咽颅底组织两次病理报告均为慢性肉芽肿性炎,经实验室确诊为啮蚀艾肯菌感染,予清创引流、口服抗生素2个月后,患者痊愈,术后随访3个月未复发。结论 鼻咽颅底感染临床少见,临床症状、影像学检查与鼻咽癌相似。啮蚀艾肯菌为罕见致病菌,发病率低。诊治上,需结合病理学、病原学检查正确诊断,及早清创引流、选取合适的抗感染药物。

    Abstract:

    Objective To summarize the diagnostic and therapeutic experience of a case about nasopharyngx and skull base infection caused by Eikenella corrodens, to improve the understanding of this bacterial infection. Methods The case data of a patient with nasopharyngx and skull base infection caused by eikenia rodentis suspected of nasopharyngeal carcinoma were analyzed retrospectively, and the literature was discussed. Results The endoscopic examination, imaging examination and laboratory examination were improved in this case. The two pathological reports were chronic granulomatous inflammation. The laboratory confirmed the infection of Eikenella corrodens.After debridement and drainage and tow-month oral antibiotics, the patient recovered and was followed up for three months without relapse. Conclusion Nasopharyngx and skull base infection is rare in clinic. The clinical symptoms and imaging are similar to those of nasopharyngeal carcinoma. The incidence rate of Eikenella corrodens is very low. In terms of diagnosis and treatment, correct diagnosis should be combined with pathological and etiological examination.The debridement and drainage and appropriate anti infective drugs should be selected as soon as possible.

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  • 收稿日期:2021-09-22
  • 最后修改日期:2021-11-20
  • 录用日期:2021-11-24
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