Abstract:Objective To compare the surgical effects of carbon dioxide laser and conventional cold instruments for resection of benign vocal cord lesions. Methods A total of 200 patients with benign vocal cord lesions treated in Huili People's Hospital of Sichuan Province from December 2018 to December 2020 were selected and divided into group A (100 cases) and group B (100 cases) according to double-blind method. Group A received conventional cold instrument treatment, group B received CO2 (2 subscript, same below) laser resection, postoperative visual scintigraphy, acoustic analysis and VHI (speech impairment index) were used to evaluate each group.Results There were no significant differences in nodule, polyp, cyst and mucosal leukoplakia between the two groups (P>0.05). The scintillation noise, voice shaking and fundamental frequency of group A were all lower than those of group A before operation 3 months after operation, and the MPT was higher than that before operation 3 months after operation (P<0.05). The scintillation noise, voice shaking and fundamental frequency of group B were lower than those of group B before operation 3 months after operation, and the MPT of group B was higher than that before operation 3 months after operation (P<0.05). There were no significant differences in scintillation noise, voice shaking, fundamental frequency and MPT between the two groups before and 3 months after operation (P>0.05). The body, function, emotion and total of VHI in group A 3 months after operation were lower than those in group A before operation (P<0.05). The body, function, emotion and total of VHI in group B 3 months after operation were lower than those in group B before operation (P<0.05). There were no significant differences in body, function, emotion and total VHI between the two groups before and 3 months after operation (P>0.05).Conclusion Both surgical techniques have good results in treating benign vocal cord lesions, but each has its advantages and disadvantages.