Abstract:Relapsing Polychondritis(RP) is a rare immune multisystem disease mainly involve cartilage and protein-polysaccharide-rich tissues. Clinical manifestations of RP vary greatly due to the different involved tissues. There is still no specific auxiliary examination to be used as a means of effective diagnosis, which makes clinical diagnosis difficult. Patients with airway involvement can be hidden onset and their symtoms are not typical, making it easy for patients to be misdiagnosised and miss diagnosised. But the progresse of RP with airway involvement is rapidly. When it comes to its late condition, patients’ throut and trachea would be narrow. Treatment with advanced laryngeal stenosis is quite intractable and has a poor prognosis.,making it more challengable for airway management. Thus for RP patients with airway involvement, clinicians should identify RP as far as possible at its early condition and measures should be taken not only for systemic treatment but also for management of the airway. A review of the treatment progress of Relapsing Polychondritis with airway involvement is presented in this paper , hoping to provide reference for clinicians.