Abstract:Objective To analyze the clinical characteristics of childhood cholesteatoma, explore the surgical indications and clinical efficacy of transcanal endoscopic ear surgery for childhood cholesteatoma, and provide clinical reference for the treatment of these diseases.Methods Clinical data of 20 children with middle ear cholesteatoma treated via transcanal endoscopic approach from Sept 2017 to Oct 2020 in our institute were retrospectively analyzed. Their age ranged from 3 to 14 years old with an average of 7±0.5. Preoperative high-resolution computed tomography (HRCT) of temporal bone revealed that their lesions were all within the middle ear. Transcanal endoscopic approach was adopted to resect the cholesteatoma in all cases and simultaneous artificial ossicle reconstruction was performed for the patients with destruction of auditory ossicular chain. The therapeutic effect was evaluated.Results Medical history, preoperative endoscopic and audiologic examinations as well as intraoperative findings showed congenital cholesteatoma in 18 cases (90%) (including 3 of Potsic stage II and 15 of Potsic stage III) and secondary local cholesteatoma in 2 (10%). Transcanal endoscopic ear surgery was performed successfully in all the children. They had been followed up for more than one year with an average of 34±8.0 months. Dry ear was achieved in all cases 3 months after surgery. Follow-up found no recurrence except one case (5%, 1/20) with Potsic stage III congenital cholesteatoma. This patient received reoperation under otoendoscope, and no recurrence was found for the next 26 months with follow-up visit. The preoperative average air conducted pure-tone auditory threshold was (37.3±9.3) dB and the postoperative one was (29.8±6.3) dB, which indicated significant improvement of postoperative hearing.Conclusions Congenital cholesteatoma in children is common, often invades auditory ossicular chain and needs exhaustive preoperative evaluation. With advantages of good surgical effect and low recurrence rate by providing a clear wide-angle vision, minimally invasive treatment of cholesteatoma and reconstruction of the auditory ossicular chain with a small amount of bone resection, transcanal endoscopic ear surgery is a promising remedy to treat localized cholesteatoma (Postic stage I-III) in children.