Abstract:Laryngeal squamous cell carcinoma (LSCC) is one of the common malignant tumors of the head and neck. In recent years, the incidence of the disease has been increasing gradually, but the 5-year survival rate of patients has not increased. There is an urgent need for more stable and effective prognostic evaluation indicators to guide treatment and predict prognosis. Tumor-infiltrating lymphocytes (TILs) are highly heterogeneous lymphocytes in tumor tissues, mainly T lymphocytes, which play a key role in host antigen-specific tumor immune response. A number of studies have shown that TILs are closely related to the prognosis of the patients LSCC. In this paper, the general characteristics, evaluation methods of TILs and the prognostic value of TILs in LSCC were reviewed.
