鼻内镜下等离子射频鼻后神经切断术治疗中重度变应性鼻炎疗效观察
作者:

Therapeutic effect of endoscopic plasma postnasal neurotomy for moderate to severe allergic rhinitis
Author:
  • 摘要
  • | |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • | |
    摘要:

    目的 探讨鼻内镜下等离子射频行鼻后神经切断治疗中重度持续性变应性鼻炎的疗效。方法 2015年1月—2018年1月收治中重度变应性鼻炎合并下鼻甲肥大患者80例,其中46例同时合并有鼻中隔偏曲,所有患者应用等离子射频行鼻后神经切断术,同时行下鼻甲成形术;对46例合并鼻中隔偏曲患者行鼻中隔矫正术,观察手术前后变应性鼻炎症状改善情况。结果 术后经随访1年有效率100%,2年有效率95%,3年有效率88.75%,患者术后1、2、3年VAS总评分均比术前明显好转,3年内随着年限延长,治疗有效率逐年下降,VAS总评分逐年上升(P<0.05)。结论 鼻内镜下等离子射频行鼻后神经切断联合鼻中隔矫正及下鼻甲成形术治疗中重度变应性鼻炎疗效确切,长期效果仍需要进一步研究。

    Abstract:

    Objective To investigate the therapeutic effect of endoscopic plasma postnasal neurotomy for moderate to severe persistent allergic rhinitis (PAR).Methods Eighty patients with moderate to severe PAR and hypertrophy of inferior turbinate hospitalized in our department between Jan 2015 and Jan 2018 were included. Of them, 46 were simultaneously combined with nasal septal deviation. All patients underwent endoscopic plasma postnasal neurotomy and inferior turbinoplasty. Endoscopic nasal septoplasty was simultaneously performed in the 46 patients with nasal septal deviation. The postoperative improvements of AR symptoms were observed.Results Follow-up revealed that the effective rate was 100% in 1 year, 95% in 2 years, and 88.75% in 3 years postoperatively, The overall scores of visual analogue scale (VAS) in 1 year, 2 and 3 years got improved significantly compared with those before surgery. Within 3 years, the therapeutic effect got decreased with increase of total VAS score year by year(P<0.05).Conclusions Endoscopic plasma postnasal neurotomy combined with nasal septoplasty and inferior turbinoplasty is effective for moderate and severe PAR. However, the long-term effect still needs further study.

    网友评论
    网友评论
    分享到微博
    发 布
    参考文献
    [1] Zhang Y, Zhang L. Prevalence of allergic rhinitis in China[J]. Allergy Asthma Immunol Res, 2014, 6(2):105-113.
    [2] 李超, 曹永华, 张艳廷, 等.鼻内镜下手术治疗鼻高反应性疾病进展[J].山东大学耳鼻喉眼学报, 2018, 32(1):77-81.
    [3] 李华斌.变应性鼻炎的发病机制及诊治进展[J].中华耳鼻咽喉头颈外科杂志, 2014, 49(4):374-352.
    [4] 中华耳鼻咽喉头颈外科杂志编委会鼻科组, 中华医学会耳鼻咽喉头颈外科学分会鼻科学组.变应性鼻炎诊断和治疗指南(2015年, 天津)[J].中华耳鼻咽喉头颈外科杂志, 2016, 51(1):6-24.
    [5] 刘怀涛, 马瑞霞, 闫小会, 等.鼻后神经切断术治疗高反应性鼻病的临床观察[J].中华耳鼻咽喉头颈外科杂志, 2013, 48(12):1032-1034.
    [6] 黄选兆, 汪吉宝, 孔维佳.实用耳鼻咽喉头颈外科学[M].第2版.北京:人民卫生出版社, 2008:222.
    [7] 中华医学会呼吸病学分会哮喘学组.上-下气道慢性炎症性疾病联合诊疗与管理专家共识[J].中华医学杂志, 2017, 97(26):2001-2022.
    [8] Voisin T, Borvier A, Chiu IM. Neuro-immune interactions in allergic diseases:novel targets for therapeutics[J].Int Immunol, 2017, 29(6):247-261.
    [9] 刘怀涛, 马瑞霞, 程雷.难治性变应性鼻炎的外科治疗[J].山东大学耳鼻喉眼学报, 2017, 31(3):18-21.
    [10] 杨文娟, 郭其云, 赵海红, 等.鼻内镜下鼻后神经切断术治疗变应性鼻炎临床研究[J].潍坊医学院学报, 2019, 41(3):179-181
    [11] 蔡智谋, 于超生, 文忠.鼻内镜下鼻后神经切断术研究进展[J].中国耳鼻咽喉颅底外科杂志, 2020, 26(1):106-108.
    [12] 李泳鹏.鼻内窥镜下鼻后神经切断术治疗变应性鼻炎分析[J].系统医学, 2019, 4(20):35-37.
    [13] Ikeda K, Yokoi H, Saito T, et al. Effect of resection of the posterior nasal nerve on functional and morphological changes in the inferior turbinate mucosa[J].Acta Otolaryngol, 2008, 128(12):1337-1341.
    [14] Feng M, Zeng X, Li J. House dust mite subcutaneous immunotherapy in Chinese patients with allergic asthma and rhinitis[J]. J Thorac Dis, 2019, 11(8):3616-3625.
    [15] 黄宾, 李鹏, 孟庆翔, 等.鼻内镜下鼻后神经切断术治疗中重度持续性变应性鼻炎的疗效观察[J].临床耳鼻咽喉头颈外科杂志, 2017, 31(19):1501-1503.
    [16] Kikawada T. Endoscopic posterior nasal neurectomy:an alternative to vidian neurectomy[J].Oper Tech Otolayngol Head Neck Surg, 2007, 18(4):297-301.
    [17] 谭国林.难治性变应性鼻炎的外科治疗[J].中国耳鼻咽喉颅底外科杂志, 2016, 22(1):1-4.
    [18] 陈华山, 戴富, 柳娴, 等.筛前神经阻断治疗变应性鼻炎50例临床分析[J].临床耳鼻咽喉头颈外科杂志, 2013, 27(5):268-270.
    [19] 叶实明, 张俊中, 关兵, 等.变应性鼻炎的手术治疗及临床疗效分析[J].中国中西医结合耳鼻咽喉科杂志, 2015, 23(5):328-330.
    [20] Okubo K, Kurono Y, Ichimura K, et al. Japanese guidelines for allergic rhinitis 2017[J]. Allergol Int, 2017, 66(2):205-219.
    引证文献
引用本文

薛令军,张晓锋,刘卫海,邓金虎,刘丽丽,张恩东.鼻内镜下等离子射频鼻后神经切断术治疗中重度变应性鼻炎疗效观察[J].中国耳鼻咽喉颅底外科杂志,2021,27(4):395-398

复制
分享
文章指标
  • 点击次数:81
  • 下载次数: 408
历史
  • 收稿日期:2021-06-06
  • 在线发布日期: 2021-09-02
温馨提示

本刊唯一投稿网址:www.xyosbs.com
唯一办公邮箱:xyent@126.com
编辑部联系电话:0731-84327210,84327469
本刊从未委托任何单位、个人及其他网站代理征稿及办理其他业务联系,谨防上当受骗!

关闭