咽喉反流与变应性鼻炎的相关性研究

Relationship between laryngopharyngeal reflux and allergic rhinitis

摘要:

目的 咽喉反流（LPR）与变应性鼻炎（AR）临床表现常类似，本研究的目的是探讨这两种疾病的相关性。方法 纳入2019年6月—2020年6月就诊的72例疑似LPR患者，根据24hDx-pH监测结果将患者分为LPR阳性组和LPR阴性组，用AR表评分（SFAR）（SFAR≥7分）诊断AR，探讨Dx-pH与SFAR评分的相关性及进行LPR阳性与LPR阴性组中AR患病率的比较。结果 72例疑似LPR患者有40例AR患者，LPR阳性组（32例）中有22例AR患者，LPR阴性组（40例）中有18例AR患者，LPR阳性组的SFAR评分显著高于LPR阴性组（P<0.05），LPR阳性组中AR患病率更高（P<0.05）。结论 LPR阳性组患者SFAR评分更高，LPR与AR可能具有相关性。

Abstract:

Objective To explore the correlation between laryngopharyngeal reflux (LPR) and allergic rhinitis (AR).Methods Seventy-two patients with suspected LPR who visited our outpatient department of otolaryngology between June 2019 and June 2020 were included. All the patients were divided into LPR positive group and LPR negative group according to their 24 hDx-pH monitoring results. The diagnosis of AR was established via score for allergic rhinitis (SFAR)(SFAR≥7).The prevalence rate of AR in LPR positive and negative groups was compared, and the correlation between Dx-pH and SFAR scores was studied.Results Of the 72 patients, the diagnosis of AR was established in 40, including 22 in the LPR positive group (32 cases) and 18 in the LPR negative group (40 cases). The SFAR score of LPR positive group was significantly higher than that of LPR negative group (P<0.05). The prevalence rate of AR in the LPR positive group was higher than that of the negative group (P<0.05).Conclusion The SFAR score of LPR positive group is higher than that of the LPR negative group, which suggests that LPR and AR may be relevant.