Abstract:Objective To investigate the clinical features of blindness-leading posterior sinus cyst so as to make early diagnosis and proper treatment to avoid serious visual impairment. Methods Three patients suffering from posterior sinus cysts with blindness as the first symptom were reported. Their clinical data including history, laboratory and imaging results were collected. Once the diagnosis was clear, all patients received urgent endoscopic sinus opening, cysts resection and optic nerve decompression. They were followed up postoperatively to assess visual recovery. Results The symptoms got relieved postoperatively in all 3 patients. Of them, vision recovered to light perception in one and did not improve in the other two. Conclusion In patient with distending periorbital pain and unexplained acute vision loss, the possibility of sinus cyst complicated with infection should be considered. Active imaging examination is helpful for early diagnosis, and timely surgical treatments including optic nerve decompression may facilitate the improvement of visual outcome.