Abstract:Objective To investigate the diagnosis and treatment of laryngeal obstruction caused by laryngeal reflux, it was retrospectively analyzed for the data of a patient with laryngeal obstruction caused by laryngeal reflux during pregnancy admitted in November 2019. Methods The patient was female, 29 years old, 28 weeks gestation. The patient was admitted for"hoarseness for 1 month, swallowing with dyspnea for half a month",who had Ⅲ degree laryngeal obstruction at the time of admission. Electronic laryngoscopy showed epiglottis without edema, but obvious edema of the mucosa in the posterior ring zone, vocal cord mucosal hyperemia, edema, and glottic fissure stenosis.Emergency tracheotomy and laryngeal biopsy were performed.Patients filled in the Reflux Symptom Index (RSI) for admission, 1 month after treatment, and 1 month after childbirth. Reflux symptom index(RSI) on admission,1 month after treatment, and 1 month after childbirth. Results The patient's dyspnea was relieved after tracheotomy. A pathological biopsy of the larynx revealed inflammatory cell infiltration, interstitial congestion, and no cancer cells. The RSI of the patients at admission, 1 month after treatment, and 1 month after delivery were 15,13,7.The RFS at admission,1 month after treatment and 1 month after childbirthm were 17,17,9 respectively.The catheter of the patient was extubated successfully 1 month after delivery. Conclusion Reflux is a common reaction during pregnancy, but there are few reports of laryngeal obstruction caused by reflux during pregnancy. Antacids have some safety during pregnancy, but the efficacy of the drugs needs to be further studied. Tracheotomy can be considered when the symptoms of reflux are severe in the Ⅲ、Ⅳ degree of laryngeal obstruction. The symptoms and signs caused by reflux can gradually disappear after the end of pregnancy.