扁桃体滤泡树突细胞肉瘤1例
作者:

Follicular dendritic cell sarcoma of tonsil: a case report
Author:
  • 摘要
  • | |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • | |
    摘要:

    目的 探讨扁桃体滤泡树突状肉瘤(FDCS)的临床表现、体征、诊断、病理特征、治疗方法,提高对该病的认识,减少误诊率。方法 回顾性分析1例扁桃体FDCS疾病特征,该患者因右侧口咽肿胀入院,无明显临床症状。入院后行颌面部及颈部CT检查,结果示右侧口咽部占位性病变,病理及免疫组化检查结果为FDCS,遂对该患者行右侧扁桃体及肿物扩大切除术。结果 完全切除右侧扁桃体及肿物,术后无出血、感染等并发症。术后予以放疗,随访3个月,未见复发。结论 FDCS是一种罕见的恶性肿瘤,临床症状表现无特异性,在临床工作中易被误诊,病理学及免疫组化检查是诊断该疾病的主要方法,治疗以完全性手术切除为主,术后可辅以放疗和(或)化疗。

    Abstract:

    Objective To investigate the clinical manifestations, signs, diagnosis, pathological features and treatment of tonsil follicular dendritic sarcoma, so as to improve the understanding of the disease and reduce the rate of misdiagnosis. Methods The characteristics of tonsillar follicular dendritic cell sarcoma were retrospectively analyzed. The patient was admitted to hospital on right oropharyngeal swelling without obvious clinical symptoms. After admission, CT examination of the maxillofacial region and neck was performed. The results of CT examination showed that the right oropharynx was occupied. The results of pathological and immunohistochemical examination were follicular dendrite cell sarcoma; The patient was treated by right tonsillectomy and enlarged resection. Results The right tonsil and tumor were completely excised, and had not postoperative complications such as bleeding and infection.The patient was given radiotherapy after the operation, and no recurrence after 3 months of follow-up. Conclusion Follicular dendritic cell sarcoma is a rare malignant tumor without specific clinical symptoms, which is easy to be misdiagnosed in clinical work. Pathology and immunohistochemical examination are the main methods for the diagnosis of this disease. The treatment is mainly by surgical resection, and radiotherapy and/or chemotherapy is often used after surgery.

    网友评论
    网友评论
    分享到微博
    发 布
    参考文献
    [1] Monda L,Warnke R,Rosai J. A primary lymph node malignancy with features suggestive of dendritic reticulum cell differentiation[J]. Am J Pathol,1986,122(3):562-572.
    [2] Domínguez-Malagón H,Cano-Valdez AM,Mosqueda-Taylor A,et al. Follicular dendritic cell sarcoma of the pharyngeal region:histologic, cytologic, immunohistochemical, and ultrastructural study of three cases[J]. Ann Diagn Pathol,2004,8(6):325-332.
    [3] Gounder M, Desai V, Kuk D, et al. Impact of surgery, radiation and systemic therapy on the outcomes of patients with dendritic cell and histiocytic sarcomas[J]. Eur J Cancer,2015,51(16):2413-2422.
    [4] Cakir E, Aydin NE, Samdanci E,etal. Follicular dendritic cell sarcoma associated with hyaline-vascular Castleman's disease[J]. J Pak Med Assoc,2013,63(3):393-395.
    [5] 黄永塔,莫祥兰.滤泡树突状细胞肉瘤临床病理特点及其与EB病毒关系[J].中国临床新医学,2017,10(2):110-113.
    [6] Viola P, Vroobel KM, Devaraj A, et al. Follicular dendritic cell tumour/sarcoma:a commonly misdiagnosed tumour in the thorax[J]. Histopathology,2016,69(5):752-761.
    [7] Jain P, Milgrom SA, Patel KP, et al. Characteristics, management, and outcomes of patients with follicular dendritic cell sarcoma[J]. Br J Haematol,2017,178(3):403-412.
    [8] Chan JK, Fletcher CD, Nayler SJ, et al. Follicular dendritic cell sarcoma. Clinicopathologic analysis of 17 cases suggesting a malignant potential higher than currently recognized[J]. Cancer,1997,79(2):294-313.
    引证文献
引用本文

杨洋,王建明.扁桃体滤泡树突细胞肉瘤1例[J].中国耳鼻咽喉颅底外科杂志,2021,27(1):94-96

复制
分享
文章指标
  • 点击次数:70
  • 下载次数: 208
历史
  • 收稿日期:2020-03-26
  • 在线发布日期: 2021-03-04
温馨提示

本刊唯一投稿网址:www.xyosbs.com
唯一办公邮箱:xyent@126.com
编辑部联系电话:0731-84327210,84327469
本刊从未委托任何单位、个人及其他网站代理征稿及办理其他业务联系,谨防上当受骗!

关闭