扁桃体滤泡树突细胞肉瘤1例

Follicular dendritic cell sarcoma of tonsil: a case report

摘要:

目的 探讨扁桃体滤泡树突状肉瘤（FDCS）的临床表现、体征、诊断、病理特征、治疗方法，提高对该病的认识，减少误诊率。方法 回顾性分析1例扁桃体FDCS疾病特征，该患者因右侧口咽肿胀入院，无明显临床症状。入院后行颌面部及颈部CT检查，结果示右侧口咽部占位性病变，病理及免疫组化检查结果为FDCS，遂对该患者行右侧扁桃体及肿物扩大切除术。结果 完全切除右侧扁桃体及肿物，术后无出血、感染等并发症。术后予以放疗，随访3个月，未见复发。结论 FDCS是一种罕见的恶性肿瘤，临床症状表现无特异性，在临床工作中易被误诊，病理学及免疫组化检查是诊断该疾病的主要方法，治疗以完全性手术切除为主，术后可辅以放疗和（或）化疗。

Abstract:

Objective To investigate the clinical manifestations, signs, diagnosis, pathological features and treatment of tonsil follicular dendritic sarcoma, so as to improve the understanding of the disease and reduce the rate of misdiagnosis. Methods The characteristics of tonsillar follicular dendritic cell sarcoma were retrospectively analyzed. The patient was admitted to hospital on right oropharyngeal swelling without obvious clinical symptoms. After admission, CT examination of the maxillofacial region and neck was performed. The results of CT examination showed that the right oropharynx was occupied. The results of pathological and immunohistochemical examination were follicular dendrite cell sarcoma; The patient was treated by right tonsillectomy and enlarged resection. Results The right tonsil and tumor were completely excised, and had not postoperative complications such as bleeding and infection.The patient was given radiotherapy after the operation, and no recurrence after 3 months of follow-up. Conclusion Follicular dendritic cell sarcoma is a rare malignant tumor without specific clinical symptoms, which is easy to be misdiagnosed in clinical work. Pathology and immunohistochemical examination are the main methods for the diagnosis of this disease. The treatment is mainly by surgical resection, and radiotherapy and/or chemotherapy is often used after surgery.