Abstract:Objective To investigate the prevalence of chronic rhinosinusitis and the influence of disease on quality of life among students aged from 10 to 17 years old in Changsha. Methods From Aug 2017 to Feb 2018, an epidemiological survey was conducted on 5,556 students through questionnaires and specialist physical examinations. Their quality of life was evaluated by visual analogue scale (VSA) and sino-nasal outcome-20 (SNOT-20). Results The prevalence of chronic rhinosinusitis in primary and middle school students in Changsha was 5.0% (280/5 556). Chronic rhinosinusitis caused problems in students' learning and life and affected their quality of life. The problems seriously impacting the quality of life in the affected students were in order as follows:blowing their noses, poor attention, depression, anxiety, irritability, difficulty falling asleep, and purulent nasal discharge. Conclusions The prevalence of chronic rhinosinusitis in students aged from 10 to 17 years old in primary and middle schools in Changsha is 5.0%. Chronic rhinosinusitis can cause learning and life problems for primary and middle school students, and therefore affect their quality of life.