鼻咽及口咽RosaiDorfman病1例

RosaiDorfman disease of nasopharynx and oropharynx:a case report

摘要:

目的通过RosaiDorfman病(RDD)患者1例报道，结合文献，分析其临床特征、病理学特点及诊疗方法，提高临床医师对该病的认识水平。方法回顾性分析2017年10月中国医科大学附属第一医院收治的RDD患者1例，该患者在颅底导航指引下行内镜经鼻结合经口径路鼻咽部肿物切除术。术后辅以激素治疗1个月，2019年1月再次发现舌根肿物，行舌根肿物切除术。结果患者手术顺利，术后病理确诊为RDD，局部伤口愈合良好，无出血及咽部狭窄等并发症，随访1年，未见复发。结论确诊RDD病的金标准是病理学检查，临床表现及影像学检查均无特异性。对于呼吸道梗阻、重要部位受压迫的患者，应尽早手术治疗，可术后辅以激素。需要定期随诊。

关键词:RosaiDorfman 病|窦组织细胞增生伴巨大淋巴结病|鼻咽及口咽部|3D打印|手术治疗

Abstract:

ObjectiveThrough the report of a case of Rosai Dorfman disease (RDD), combined with review of literature, the clinical and pathological characteristics, and the diagnosis and treatment methods were analyzed to improve the recognition level of clinicians.MethodsOne patient with RDD admitted to the First Affiliated Hospital of China Medical University in October 2017. Under the guidance of skull base navigation, the patient underwent "Combined Endoscopic Transnasal and Transoral Excision of nasopharynx tumor". After one month of hormone treatment, in January 2019, the tumor of the tongue root was found again and "resection of the tumor of the tongue root" was performed.ResultsThe operation of the patient was successful, and the pathological diagnosis confirmed the postoperative tumors for RDD. The local wound healed well, and no bleeding, pharyngeal stenosis and other complications. The patient was followed up for 1 year without recurrence.ConclusionsPathology is the gold standard for the diagnosis of RDD, and the clinical manifestations and imaging examination of RDD are not specific. For patients with airway obstruction and compression of important parts, surgical treatment should be carried out as early as possible, and hormone can be supplemented after operation. The patient’s regular followup is needed.

Key words:RosaiDorfman disease|Sinus histiocytosis with massive lymphadenopathy|Nasopharynx and oropharynx|3D printing|Surgical treatment