不同性别的喉癌患者血清钙离子含量差异分析

Analysis of the difference of serum calcium in laryngeal cancer patients with different genders

摘要:

目的探讨血清微量元素钙离子在不同性别喉癌患者中的含量差异。方法选取2001—2018年在青岛市市立医院接受治疗的33例女性喉癌患者进行临床分析，并随机选取60例在青岛市市立医院体检的健康女性作为对照组。另随机选取121例男性喉癌患者和121例健康男性进行临床分析。结果33例女性喉癌患者中25例患者血清钙离子水平下降，血清钙离子水平为（1.94±0.11）mmol/L，女性喉癌患者血清钙离子低于女性健康对照组的（2.31±0.11）mmol/L，经比较差异具有统计学意义（P<0.05）。男性喉癌患者血清钙离子为（2.32±0.21）mmol/L，与健康男性对照组的（2.31±0.23）mmol/L比较无统计学意义（P>0.05）。结论喉癌患者的血清钙离子水平下降可能只参与了女性喉癌的发生发展，并没有参与男性喉癌的发生发展,为临床筛查女性喉癌患者提供一定的指导意义。

Abstract:

ObjectiveTo analyze the difference of serum calcium in laryngeal cancer patients with different genders.MethodsA total of 33 female patients with laryngeal cancer who received treatment were selected for clinical analysis, and 60 healthy women who underwent physical examination were randomly selected as the control group in Qingdao Municipal Hospital from 2001 to 2018. And 121 male patients with laryngeal carcinoma and 121 healthy men were randomly selected for clinical analysis.ResultsAmong the 33 female patients with laryngeal cancer, the serum calcium level of 25 patients decreased to (1.94±0.11) mmol/L.The serum calcium of female laryngeal cancer patients was lower than that of the female healthy control group (2.31±0.11) mmol/L, and the difference was statistically significant(P<0.05). The serum calcium of male patients with laryngeal cancer was (2.32±0.21) mmol/L compared with that of healthy male control group (2.31±0.23) mmol/L. There was no significant difference in serum calcium between male patients with laryngeal carcinoma and healthy men(P>0.05).ConclusionThe decrease of serum calcium in laryngeal carcinoma may be involved in the occurrence and development of laryngeal carcinoma in women and not in men， which provides some guidance for clinical screening of female laryngeal carcinoma.