Abstract:ObjectiveTo investigate the effect of transoral CO2 laser surgery on voice status of patients with early glottic carcinoma.MethodsClinical data of 48 patients with early glottic carcinoma treated by transoral CO2 laser surgery from March 2016 to June 2019 were analyzed retrospectively. They were divided into two groups according to the surgical approaches: the anterior commissure unresected group (n=29) and anterior commissure resected group (n=19). Voice handicap index simplified Chinese version (VHI13) rating scale, strobolaryngoscopy and voice acoustic analysis were used to compare the voice function between preoperative stage and 6 months postoperative stage.ResultsCompared with the preoperative stage, their total VHI13 score and physiology score in the 6 months postoperative stage were significantly decreased. Strobolaryngoscopy exhibited weakened or disappeared mucosal waves in the anterior commissure unresected group, and anterior conglutination or compensatory articulation in the anterior commissure resected group. Voice acoustic analyses revealed postoperative increased fundamental frequency (F0), amplified fundamental frequency perturbation (jitter) and amplitude perturbation (shimmer), shortened maximal phonatory time (MPT) and reduced dysphonia severity index (DSI) in both groups. Compared with the anterior commissure resected group, the parameter of Shimmer was significantly decreased in the unresected group, accompanied by more prolonged MPT and higher DSI.ConclusionsThe subjective voice quality of patients with glottic carcinoma after transoral CO2 laser surgery is improved to a certain extent compared with that before surgery. Resection of anterior commissure is closely related to the postoperative vocal cord shape and voice quality.
