Abstract:ObjectiveTo summarize the experience in tracheal defect repair for thyroid cancer with cervical trachea invasion so as to improve the effect of intraoperative repair.MethodsFrom Aug 2011 to Feb 2019, thirtytwo patients suffering from thyroid cancer with cervical trachea invasion were surgically treated. Of them, 6 cases received shave excision of the invaded outer wall of trachea, 8 were treated with tracheal sleeve resection plus endtoend anastomosis, 6 with sternocleidomastoid clavicular periosteal flap, 8 with sternocleidomastoid clavicular periosteal flap combined biofilm, 2 with free forearm flap and autologous cartilage transplantation, and 2 with tracheal fistulization and phase II repair.ResultsAmong the 6 patients with shave excision of tracheal outer wall, one got tracheal fistula on the 6th day after surgery and was discharged after dressing change. Of the remaining 26 patients, twentyfour (92.3%) completely restored their respiratory function in 6 months after surgery, extubation was not achieved in one patient with free forearm flap and autologous cartilage transplantation due to local tracheal stenosis and phlegm blockage, and another patient with sternocleidomastoid clavicular periosteal flap combined biofilm due to bilateral vocal cord paralysis and tracheal local collapse.ConclusionTo obtain high surgical successful rate and good treatment effect, appropriate tracheal resection and proper repair method of tracheal defect should be selected based on the invasion range for the patients suffering from thyroid cancer with tracheal invasion.