Abstract:ObjectiveApplication of perforator flap is the major repair means in repair for tissue defects after resection of head and neck tumor. The forearm flap and the free anterolateral thigh flap are the important workhorse flaps. Local flaps adjacent to head and neck including the supraclavicular artery island flap, the thoracoacromial artery perforator flap and the submental flap have become increasingly popular. Future considerations of head and neck reconstruction are digitalization and precision. Function preservation of donor site and organ function reconstruction of recipient site are also future directions. In recent years, tissueengineered grafts and the complex printing of viable tissues and organs have been explored as the potential application of 3D printing in repair for tissue defects after resection of head and neck tumor.