右美托咪定应用于上呼吸道手术麻醉的临床研究进展

Progress of clinical research on the application of dexmedetomidine in anesthesia of rhinolaryngology surgery

摘要:

目的近年来，鼻咽喉等上呼吸道疾病发病率呈上升趋势，临床常采用内镜手术治疗，由于手术部位的特殊性，导致患者有极其不愉快的体验，影响预后。而一种有效的麻醉药对鼻、咽、喉手术及术后恢复十分重要。右美托咪定（DEX）具有独特的镇静、抗交感及镇静作用，本文就麻醉药的药理学特性、对机体的影响，以及在鼻、咽、喉手术麻醉中的应用进展作一综述，为提高患者麻醉舒适度、促进患者术后康复提供帮助。

关键词:鼻咽喉手术麻醉|右美托咪定|临床研究

Abstract:

ObjectiveLately, the incidence of nasal, pharyngeal, laryngeal and other upper respiratory tract patients is a rising trend. The patients are often treated by endoscopic surgery. Due to the particularity of the anatomical structure, patients have extremely unpleasant experience, which affects the prognosis. Therefor, an effective anesthetic is very important for the treatment and postoperative recovery of nasopharyngeal surgery. Dexmedetomidine has unique sedative, antisympathetic and analgesic effects. This article reviews the pharmacologic characteristics of dexmedetomidine, its impact on the body, and its application progress in the anesthesia of rhinolaryngology surgery. It is helpful to improve the comfort of anesthesia and promote the postoperative recovery of patients.

Key words:Anesthesia for rhinolaryngology|Dexmedetomidine|Clinical research