鼻内镜下咽鼓管吹张注药治疗急性分泌性中耳炎的临床研究
作者简介:

林雯超,Email:linwenanna@126.com

基金项目:

上海市黄浦区科研项目(HKQ201802)。


Treatment of acute secretory otitis media by transnasal endoscopic eustachian tube insufflation with simultaneous drug injection
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    摘要:

    目的探讨鼻内镜下咽鼓管吹张注药联合口服抗生素及黏液促排剂治疗急性分泌性中耳炎的临床效果。方法选取2018年8月—2019年10月门诊急性分泌性中耳炎患者共135例(158耳)作为研究对象,随机分为对照组、常规组及研究组。其中对照组42例(50耳):接受药物治疗;常规组45例(53耳):接受药物治疗+鼓膜穿刺术;研究组48例(55耳):接受药物治疗+鼻内镜下咽鼓管吹张注药。经治疗后观察2个月,研究终点时对3组疗效、纯音听阈测试(PTA)、鼓室图变化、有无并发症、复发率及不良反应的数据进行统计学分析。结果3组总有效率比较,差异均具有统计学意义(P均<0.05);3组的复发率比较差异均无统计学意义(P均>0.05)。结论鼻内镜下咽鼓管吹张注药联合口服用药治疗法,安全有效,对急性分泌性中耳炎临床治疗效果好,并发症少及患者接受程度高等优点,值得临床推广。

    Abstract:

    ObjectiveTo evaluate the clinical effect of tansnasal endoscopic eustachian tube insufflation and simultaneous drug injection combined with oral administration for the treatment of acute secretory otitis media (ASOM).MethodsA total of 135 outpatients with ASOM from Aug 2018 to Oct 2019 were selected. They were randomly allocated to control group (42 patients, 50 ears),routine group (45 patients, 53 ears) and research group (48 patients, 55 ears). The patients in the research group were given tansnasal endoscopic eustachian tube insufflation and simultaneous drug injection combined with oral administration, those in the routine group were given auripuncture combined with oral administration, while those in the control group were given oral administration only. Two months after treatment, the clinical effect, changes of tympanogram, average airconducted puretone auditory thresholds, complications and adverse events, recurrence rates among the three groups were observed and compared.ResultsResults The differences of total effective rate among the three groups were statistically significant (all P<0.05), while those of recurrence rates were statistically insignificant (all P>0.05).ConclusionWith advantages of definite clinical effect, good safety, less complications and high patient acceptance, transnasal endoscopic eustachian tube insufflation and simultaneous drug injection combined with oral administration is worthy of clinical promotion for the treatment of ASOM.

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林雯超.鼻内镜下咽鼓管吹张注药治疗急性分泌性中耳炎的临床研究[J].中国耳鼻咽喉颅底外科杂志,2020,26(2):153-157

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