10例马德龙病Ⅰ型临床分析并文献复习

Madelung's disease (type I):10 cases reports and review of the literature

摘要:

目的探讨马德龙病（Madelung’s disease）的临床特点及诊断和治疗方法，减少该病的误诊误治。方法收集2016年12月—2018年6月笔者所在医院及外出会诊治疗的10例经外科手术治疗的马德龙病Ⅰ型患者的临床资料并结合文献进行复习。10例患者均为男性，年龄42~57岁，平均51岁。病变集中在颈项部、枕部，可伴有呼吸困难、吞咽不适、上臂疼痛、声音嘶哑及偏头困难等症状。所有患者均有长期饮酒史。结果所有患者均采取脂肪切除术，术后随访6个月至2年，随访期间无1例复发。结论马德龙病主要发生在长期饮酒史的中年男性，该病多伴有肝功能异常，手术治疗是马德龙病目前最有效的治疗方法，病变范围较大患者需采用分次手术治疗。

Abstract:

Abstract:ObjectiveTo explore the clinical characteristics, diagnosis and treatment of type I Madelung’ s disease and reduce the misdiagnosis and mistreatment.MethodsThe clinical data of 10 patients with type I Madelung' s disease treated by surgery were collected from December 2016 to June 2018. The patients were collected from the hospital where the author worked，and went out for consultation and treatment. 10 Case were analyzed and the literature was reviewed. All the 10 patients were male, aged 42-57 years, with an average age of 51 years. The lesions are concentrated in the neck and occiput, accompanied by dyspnea, dysphagia, upper arm pain, hoarseness, difficulty in tilting the head, and other symptoms. All patients had a long history of alcohol consumption.ResultsAll patients underwent fat resection and were followed up for 6 months to 2 years without recurrence.ConclusionsMadelung’ s diseasemainly occurs in middleaged men with a long history of drinking, and the disease is often accompanied by abnormal liver function. Surgical treatment is the most effective treatment for Madelung’ s disease at present, and patients with a wide range of lesions need to be treated by multiple surgeries.