T1aN0M0声门型喉癌术后发声功能评估

Evaluation of postoperative vocal function in patients with T1aN0M0 glottic cancer

摘要:

目的分析T1aN0M0声门型喉癌患者术后嗓音障碍程度。方法对70例T1aN0M0声门型喉癌患者术后进行嗓音研究，采用SPSS 17.0统计软件进行统计学分析。结果70例患者均为声门型鳞状细胞癌（T1aN0M0），其中21例采用CO2激光手术，49例采用低温等离子刀手术。CO2激光组中位生存时间为35个月，低温等离子刀组中位生存时间为26个月。主观听感知方面：CO2激光组术后嗓音障碍程度轻于低温等离子刀组；客观参数方面：两两比较显示基频微扰（Jitter）敏感度最高，差异具有统计学意义（P＜0.05）；参数相关性检验显示：谐噪比（HNR）与主观G相关性最好。结论所选声学主、客观参数一致性较好，CO2激光术后患者主观嗓音评估优于低温等离子刀。

Abstract:

Abstract:ObjectiveTo evaluate the postoperative vocal function in patients with T1aN0M0 glottic cancer.MethodsEvaluation of the voice quality was performed in 70 postoperative patients with T1aN0M0 glottic cancer. SPSS 17.0 statistical analysis software was used.ResultsOf all the 70 patients with glottic squamous cell carcinoma at T1aN0M0, 21 cases were surgically treated with CO2 laser and 49 with lowtemperature plasm radiofrequency.The median survival time of CO2 laser group was 35 months and that of the lowtemperature plasm radiofrequency group was 26 months.Subjective perceptual evaluation of voice quality showed that the degree of voice disturbance in the CO2 laser group was less than that of the lowtemperature plasm radiofrequency group.Objective analyses revealed no difference in fundamental frequency (F0) between the two groups but consistency of parameter of hoarseness (G) and the other objective parameters. Pairwise comparisons showed that Jitter had the highest sensitivity and correlation test found that noisetoharmonics ratio had the best correlation with G.ConclusionWith good consistency between subjective perceptual and objective parameters, the patients surgically treated with CO2 laser have better voice quality than those treated with lowtemperature plasm radiofrequency.