变应性鼻炎的发病机制与精准治疗

Allergic rhinitis: pathogenesis and precision medicine

摘要:

目的变应性鼻炎临床上以鼻痒、喷嚏和流涕为典型特征，是一种变应原特异性IgE介导的鼻黏膜慢性炎症，目前治疗包括变应原回避、药物治疗、免疫治疗和手术治疗。基于不同免疫表型的精准治疗代表了变应性鼻炎治疗的未来方向。

Abstract:

Abstract:ObjectiveAllergic rhinitis, a chronic inflammatory cascade in nasal mucosa mediated by allergenspecific IgE, is clinically characterized by pruritus, sneezing and rhinorrhoea. Current therapeutic strategy includes allergen avoidance, pharmacotherapy, immunotherapy and surgery. Precision medicine, based on immunological phenotypes, indicates the future therapeutic direction for the treatment of allergic rhinitis.