神经导航血管融合成像辅助显微手术切除矢状窦旁脑膜瘤
作者简介:

王志刚,Email:wzg1110@126.com

基金项目:

山东省重点研发计划(2018GSF118107);青岛市民生科技计划 (186197nsh)。


Microsurgical removal of parasagittal meningiomas assisted with neuronavigation and vascular fusion imaging technique
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    摘要:

    目的探讨神经导航血管融合成像技术辅助显微外科手术切除矢状窦旁脑膜瘤的临床价值。方法回顾分析2016年1月~2018年6月采用神经导航血管融合成像技术辅助显微外科治疗的31例累及矢状窦的脑膜瘤患者的手术效果和预后情况。结果切除程度:Simpson 1级切除16 例(51.61%);Simpson 2级10 例(32.26%);Simpson 3级4例(12.91%);Simpson 4级1例(3.22%)。肢体麻木无力改善12例,2例无改善,2例加重;2例头痛症状持续,余5例症状消失;2例癫痫症状完全缓解,余1例需持续口服抗癫痫药物控制;体检发现肿瘤的患者术后无神经功能障碍。术后病检示Simpson 1级切除患者病理分级均为WHO分级I级;Simpson 2级切除中,2例为WHO分级II级,余8例为WHO分级I级;Simpson 3级切除中,3例为WHO分级II级,1例为WHO分级III级;Simpson 4级切除的1例为WHO分级III级;15例未达到Simpson 1级切除的患者术后予以常规放射治疗。随访3~34个月,中位随访时间15.6个月,复发1 例,为WHO分级II级,予以再次手术治疗,术后已随访4个月,未见复发。结论对肿瘤及肿瘤基底部硬膜全切,术后有较低复发率,神经导航血管融合成像技术可指导术前手术计划、切口范围,为掌握肿瘤基底部矢状窦特征,术中处理矢状窦附着处肿瘤提供积极的参考依据,提高手术安全性,值得临床推广。

    Abstract:

    ObjectiveTo evaluate the clinical value of neuronavigation and vascular fusion imaging technique in microsurgical resection of paragittal sinus meningiomas.Methods31 cases of meningioma involving sagittal sinus were treated microsurgically with assistance of neuronavigation and vascular fusion imaging in our hospital from Jan. 2016 to Aug. 2018. The surgical effect and prognosis were analyzed retrospectively.ResultsOf the 31 cases, Simpson grade 1 resection was achieved in 16 cases (51.61%), grade 2 in 10 (32.26%), grade 3 in 4 (12.91%) and grade 4 in 1 case (3.22%). Limb numbness was improved in 12 cases, not improved in 2, and exacerbated in 2. Headache disappeared in 5 cases and sustained in 2. Epilepsy got remitted completely in 2 cases, and controlled with continuous oral antiepileptic drug in 1. Postoperative pathology revealed grade I in all the 16 cases with Simpson grade 1 resection, grade II in 2 and grade I in 8 of the 10 cases with Simpson grade 2 resection, grade II in 3 and grade III in 1 of the 4 cases with Simpson grade 3 resection, and grade III in the one with Simpson grade 4 resection, according to the World Health Organization (WHO) grading system. All patients without Simpson grade 1 resection received postoperative routine radiotherapy. The median followup time was 15.6 months, and recurrence occurred in one case of WHO grade II. Reoperation was performed to this patient and no recurrence was found after 4 months of followup.ConclusionWith advantages of low recurrence rate via resecting tumor and its basal dura, guiding the preoperative plan and the incision range, grasping the characteristics of sagittal sinus at the base of the tumor, and improving safety via providing positive reference for the removal of tumor attaching the sagittal sinus, neuronavigation and vascular fusion imaging technique has good values of popularization and application.

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田海龙,危兆胜,钟原,刘斌,王超超,王志刚.神经导航血管融合成像辅助显微手术切除矢状窦旁脑膜瘤[J].中国耳鼻咽喉颅底外科杂志,2019,25(3):257-260

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  • 在线发布日期: 2019-06-30
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