经眶额窦入路切除前颅底中线区脑膜瘤
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张晓华,Email:zxh1969@aliyun.com

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 国家自然科学基金青年项目(81701201)。


 Transorbitalfrontal sinus approach for the treatment of midline anterior cranial fossa meningiomas
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    摘要:

     目的总结经眶额窦入路切除前颅底中线区脑膜瘤手术技巧及疗效。方法收集2017年1月~12月上海交通大学医学院附属仁济医院神经外科6例前颅底中线区脑膜瘤患者的临床资料,其中男性2例,女性4例;年龄40~67岁,中位年龄54.5岁,均采用经眶-额窦入路切除肿瘤。结果6例患者中5例肿瘤位于前颅底嗅沟区,其中1例累及筛窦;1例肿瘤位于鞍结节、鞍隔。6例患者中肿瘤最大径均在4 cm内。4例肿瘤获Simpson II级切除,2例患者获Simpson I级切除。1例患者术后发生了脑脊液鼻漏,行腰大池引流5 d后患者脑脊液鼻漏消失。所有患者术后均恢复可,未出现发热及感染征象。结论经眶额窦入路是一种便捷、有效而且并发症较少的微创手术入路,因其可早期处理前颅底硬脑膜来源的血供,尤其适用于前颅底中线区脑膜瘤的治疗。

    Abstract:

     ObjectiveTo investigate the microsurgical technique and outcome of midline anterior cranial fossa meningiomas via transorbitalfrontal sinus approach.MethodsClinical data of 6 patients with midline anterior cranial fossa meningiomas, who underwent tumor resection via transorbitalfrontal sinus approach in our department from Jan 2017 to Dec. 2017, were recorded and analyzed retrospectively. Of them, 2 were male and 4 were female, with an age range of 40 to 67 years (median age 54.5 years).ResultsThe tumors were located at the olfactory groove in 5 cases with involvement of the ethmoid sinus in one, while the other one was located at tuberculum and diaphragma sellae. The maximal diameters of the tumors were all within 4 cm. Simpson Grade II resection was achieved in 4 cases, and Simpson Grade I resection in the other 2. Cerebrospinal fluid rhinorrhea occurred in one patient. With continuous lumbar cistern drainage for 5 days, the cerebrospinal fluid rhinorrhea disappeared. All the patients got recovered uneventfully without complications such as fever or infection.ConclusionWith advantages of convenience, high efficiency, minimal invasion and few complications, the transorbitalfrontal sinus approach is especially suitable for the treatment of midline anterior cranial fossa meningiomas as the tumor blood supply originated from the dura mater of the anterior skull base can be processed at early stage.

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郭烈美,徐天启,高卫真,贾锋,殷玉华,王宇,张晓华. 经眶额窦入路切除前颅底中线区脑膜瘤[J].中国耳鼻咽喉颅底外科杂志,2018,24(4):303-308

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  • 在线发布日期: 2018-08-30
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