Abstract:ObjectiveTo explore the clinical characteristics, diagnosis and treatment of infantile nasal hamartoma.MethodsClinical data including clinical symptoms, local signs, imaging manifestations, histopathological characteristics, diagnosis, differential diagnosis and treatment strategies of five infants with nasal hamartoma confirmed by pathology in our department were analyzed retrospectively.ResultsAll patients showed unilateral nasal obstruction，accompanied by varying degrees of cough when feeding, snoring suffocation when sleep and so on. One patient showed progressive growth of tumor within two months, four of them showed no significant increase of tumor size. One patient had ipsilateral posterior nostril stenosis. Image examinations showed that tumors were located in unilateral nasal cavity and ethmoidal sinus in 2 cases, and unilateral nasal cavity, ethmoidal sinus and nasopharynx in 3. Three patients showed skull base bone defect, and two patients showed ipsilateral orbital wall bone destruction. Three of them showed spotlike, striplike highdensity calcification with expansion of the surrounding bone wall. Nasal septum was significantly compressed to contralateral nasal cavity in all patients. Four patients received complete removal and one with three times removals. No evidence of tumor recurrence was found during followup.ConclusionsInfantile nasal hamartoma is a rare benign tumor of nasal cavity. The patients usually seek medical advice due to stuffy nose. Surgery is the mainstay of treatment modality for this tumor. With advantages of precise visualization, minimal invasion, few complication and rapid postoperative recovery, transnasal endoscopic technique is helpful in completely removing the nasal masses in most cases.
