ObjectiveTo evaluate the applicative value of imageguided system (IGS) in endoscopic sinus surgery (ESS).MethodsClinical data of the patients received ESS in our department with (n=239, IGS group) or without (n=298, NIGS group) assistance of an IGS from Feb 2008 to Feb 2016 were analyzed retrospectively. Their durations of surgery and incidences of complications were recorded and compared.ResultsThe mean duration of surgery of the IGS group was significantly shorter than that of the NIGS group (P<0.001). There were significant differences in the incidences of intraorbital hematoma and total complication between the two groups (P=0.036 and 0.002, respectively).ConclusionsApplication of magnetic navigation system in ESS can significantly shorten duration of surgery, decrease incidence of complication, and therefore improve surgical accuracy and safety. Imageguided system has high applicative value in ESS, and its routine utilization may benefit more patients who need ESS.