Abstract:ObjectiveToprovidefoundation for propertreatment course durationof intravenous administration for sudden sensorineural hearing loss(SSHL) via comparing the administration course and clinical effect inpatients with different audiometric curves.Methods82 cases(92 ears) of SSHL were given routine treatment including microcirculation improvement, thrombolysis, glucocorticoid and neurotrophy. Their effect and treatment course of SSHL with different audiometric curveswere compared.ResultsThe total effective rate of patientswith hearing lossatlow to moderate frequencies was 84.62%, and the difference between the effective rate with treatment duration of 7 days and that of 14 days was statistically insignificant (P>0.05).The total effective rate of patientswith hearing lossat all frequencies was59.70%, and the difference between the effective rate with treatment duration of 7 days and that of 14 days was statistically significant (P<0.05). The total effective ratesatmoderateto high frequencies and high frequencies were20% and 57.14%respectively.ConclusionThe SSHLpatients withhearing lossatlow to moderate frequencies mayhave high possibility of recovery within 7 days of intravenous administration, while those with all frequenciesmay get recovered in 7 to 14 days of administration.