Abstract:ObjectiveTo analyze the therapeutic effect of medial sphenoid wing meningioma with microsurgical treatment and factors affecting the extent of resection.MethodsClinical data of 127 patients suffering from medial sphenoid wing meningioma resected microsurgically in our department between Nov 1985 and Oct 2009 were analyzed retrospectively. The factors that might affect the extent of tumor resection including tumor size, cavernous sinus invasion, internal carotid artery and its branches adherence and texture of tumor were analyzed statistically.ResultsThere was no operative mortality. Total removal of meningioma was achieved in 104 patients with a total removal rate of 81.9%. Followup was got in 120 cases with an average period of 81.6 months. 7 patients were lost to followup. The mean quality of life score (KPS score) was 90.6 points. 10 patients experienced recurrence among 98 total removal cases with a recurrence rate of 10.2%. 10 patients experienced progression among 22 subtotal removal cases and the rate was 45.4%. Univariate analysis showed that the cavernous sinus invasion, adhesion to carotid artery and its branches as well as tumor size negatively affected tumor removal, regardless of the tumor texture.ConclusionsThe longterm outcomes of medial sphenoid wing meningioma can be satisfied by microsurgical treatment and the first surgery to completely remove the tumor is crucial for prognosis. Tumor invasion of the cavernous sinus, internal carotid artery and its branches adhesion and tumor size are major factors affecting tumor removal.
