Abstract:Objective:To evaluate the effects of free composite flap transplantation on reconstruction of postoperative defects of head and neck..Methods:Clinical data of 101 consecutive free flap transfers performed in 100 patients from 2003 to 2012 was studied retrospectively. Accoding to the donor sites, the free flaps included free radial forearm flaps (n=61), latissimus dorsi flaps (n=18), free fibula flaps (n=7), rectus abdominis flaps (n=2), anterolateral thigh flaps (n=10), iliac bone flaps (n=2), and scapular flaps (n=1). The reconstruction sites included oral region (n=47), oropharyngeal region (n=16), mandible region (n=9), maxillofacial region (n=20), neck region (n=6), neck and back region (n=2). To observe the healing of free tissue flap transplantation. Results:All the patients were followed up for 2 months to 5 years postoperatively. Of all the 101 flaps, 98 survived and necrosis occurred in 3. The total survival rate of flaps was 97.03%, with a postoperative complication rate of 11.8%(12/101). The patients were generally satisfied with their shape and function. Conclusions:With various donor tissues, free tissue flap transplantation is reliable and safe in the reconstruction of postoperative defects in head and neck.