Abstract:Objective To summarize the clinical and histopathological characteristics of proliferative myositis, and to study its diagnosis, treatment and prognosis. Methods The clinical features, histopathological characterristics, diagnosis, treatment and prognosis of one case of proliferative mysositis arising from the sternocleindomastoidal muscle were analyzed retrospectively. The relative literature was reviewed. Results Proliferative myositis was a rare, benign, rapidly growing disease of the skeletal muscle. It had specific histopathological characteristics. There were giant ganglionlike cells and a large number of spindleshape fibroblastic cells infiltrated in the infiltrated skeletal muscle. It could be cured by conservative surgical excision. The lesion could even be observed because of its selflimiting and selfhealing tendency. The tumor of this case didn't recur during the followup period. Conclusion Proliferative myositis is a benign disease which requires pathological evaluation to confirm the diagnosis and can be cured by conservative excision. The lesion can even be observed.