原发性颅底软骨肉瘤CT和MRI诊断

CT and MRI diangnosis of primary chondrosarcoma at skull base

摘要:

目的:分析原发性颅底软骨肉瘤的CT和MRI表现，探讨CT和MRI在颅底软骨肉瘤中的诊断价值。方法:搜集经病理组织学证实的9例颅底软骨肉瘤，全部病例均行CT和MRI平扫及增强。结果:9例CT平扫表现为等或略低密度的分叶状或类圆形软组织肿块，伴有不同程度的钙化，且形态不规则，呈散在沙粒样或弧形及粗糙团块状，同时合并骨质破坏；增强后病灶呈非均匀强化。MRI检查T1WI呈等低信号混杂影，T2WI呈高低信号混杂影，肿瘤内钙化在T1WI、T2WI均为无信号区，增强扫描明显不均匀性强化。结论:颅底软骨肉瘤有较特有的CT和MRI影像学表现，是诊断颅底软骨肉瘤的有效方法。 

Abstract:

OBJECTIVE:To analyze CT and MRI features of primary chondrosarcoma at skull base, and to evaluate the value of CT and MRI in the diagnosis of this tumor. METHODS:Nine patients suffering from pathologyconfirmed primary chondrosarcoma at skull base were enrolled in the study. Plain and enhanced CT and MRI were performed in all patients.Imaging findings were analyzed. RESULTS:Plain CT scan showed lobulate or cycloidal mass with calcification of different degrees accompanied with osseous destruction in all 9 patients. On enhanced CT, the tumors were inhomogeneously intensified.On MRI, the tumors were displayed as turbid masses with low or iso signal on T1WI and inhomogeneous highsignal on T2WI with blanksignal calcified foci. Heterogeneous enhancement was observed in all cases on enhanced MRI. Changes in signal and density were in agreement with pathological results. CONCLUSION:CT and MRI are useful for the diagnosis of primary chondrosarcoma at skull base due to their specific imaging features.