目的〓〖HT5”SS〗探讨前庭导水管扩大致突发性耳聋的治疗方案及疗效。〖HTH〗方法 分析2011年1月~2011年12月住院治疗的7例因前庭导水管扩大致突发性耳聋患儿的临床资料。根据入院前听力损失程度的不同分为两组，分别采用不同的治疗方案。对轻、中度突聋患儿采用银杏叶提取物加泼尼松治疗；对重度、极重度突聋患儿采用单唾液酸四己糖神经苷脂加泼尼松治疗，观察其疗效。结果 在听力损伤为轻、中度时，两种治疗方案没有显著差别；但听力损伤为重度、极重度时，用单唾液酸四己糖神经节苷脂加糖皮质激素治疗，听力改善效果比较明显。结论 采用单唾液酸四己糖神经节苷脂加糖皮质激素治疗因前庭导水管扩大导致突发性耳聋特别是重度、极重度聋效果明显。
Objective To investigate the treatment option and efficacy of sudden deafness caused by enlargement of vestibular aqueduct. Methods 7 children with sudden deafness caused by enlargement of vestibular aqueduct from Jan 2011 to Dec 2011 in our department were enrolled in this study. The patients were divided into two groups according to the level of hearing loss before admission, and received different treatment. Ginkgo biloba extracts and glucocorticoids were applied to patients with mild or moderate hearing loss; gangliosides GMI and glucocorticoids to those with severe or profound hearing loss. The efficacy was observed. Results There was no significant difference between the effects of the two kinds of treatment when the level of hearing loss was mild or moderate. However, as for children with severe and profound hearing loss, the hearing was significantly improved when using Gangliosides GMI and glucocorticoids. Conclusion Gangliosides GMI and glucocorticoids have obvious significant efficacy especially in the treatment of severe and profound sudden deafness caused by enlargement of vestibular aqueduct.
郝剑萍 师天祥 闫文斐 折萍.前庭导水管扩大致突发性耳聋的临床治疗体会[J].中国耳鼻咽喉颅底外科杂志,2012,18(5):377-380复制